Romidepsin
Generic name: romidepsin [ ROE-mi-DEP-sin ]
Brand name: Istodax
Dosage forms: intravenous powder for injection (10 mg); intravenous solution (5 mg/mL)
Drug class:Histone deacetylase inhibitors
What is romidepsin?
Romidepsin is used to treat T-cell lymphoma affecting the skin (cutaneous T-cell lymphoma).
Romidepsin is given after at least one other cancer treatment did not work or has stopped working.
Romidepsin may also be used for purposes not listed in this medication guide.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
Before taking this medicine
Tell your doctor if you have ever had:
heart problems or a heart rhythm disorder;
long QT syndrome (in you or a family member);
kidney disease;
liver disease (especially hepatitis B);
an electrolyte imbalance (such as high or low levels of potassium or magnesium in your blood); or
You may need to have a negative pregnancy test 7 days before starting this treatment.
Both men and women using romidepsin should use effective birth control to prevent pregnancy. Men should use condoms. Romidepsin can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 month after your last dose. Tell your doctor right away if a pregnancy occurs.
Romidepsin can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.
Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
You should not breastfeed while using this medicine, and for at least 1 week after your last dose.
How is romidepsin given?
Romidepsin is injected into a vein by a healthcar...
