Regorafenib

Generic name: regorafenib [ RE-goe-RAF-e-nib ]
Brand name: Stivarga
Dosage form: oral tablet (40 mg)
Drug classes:Multikinase inhibitors, VEGF/VEGFR inhibitors

Medically reviewed by Drugs.com on Mar 3, 2022. Written by Cerner Multum.

What is regorafenib?

Regorafenib is used to treat colorectal cancer and liver cancer. It is also used to treat a rare type of tumor that can affect the esophagus, stomach, or intestines.

Regorafenib is usually given after other cancer medications have been tried without success.

Regorafenib may also be used for purposes not listed in this medication guide.

Warnings

Use birth control to prevent pregnancy, whether you are a man or a woman. Avoid pregnancy for at least 2 months after you stop using regorafenib.

Regorafenib can cause serious or life-threatening liver problems. Call your doctor at once if you have nausea, vomiting, sleep problems, dark urine, or jaundice (yellowing of the skin or eyes).

Before taking this medicine

Tell your doctor if you have ever had:

• liver disease;

• high blood pressure;

• a bleeding or blood clotting disorder;

• heart disease, chest pain; or

• if you recently had surgery or plan to have surgery.

Both men and women using this medicine should use effective birth control to prevent p...