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Rifapentine
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Rifapentine

Generic name: rifapentine [ RIF-a-PEN-teen ]
Brand name: Priftin
Dosage form: oral tablet (150 mg)
Drug class:Rifamycin derivatives

Medically reviewed by Drugs.com on Nov 30, 2021. Written by Cerner Multum.

What is rifapentine?

Rifapentine is an antibiotic that fights bacteria.

Rifapentine is used together with other medicines to treat active tuberculosis (TB) in adults and children who are at least 12 years old.

Rifapentine is also used to keep inactive (latent) TB from becoming active in adults and children who are at least 2 years old.

Rifapentine must always be used in combination with other tuberculosis medications.

Rifapentine may also be used for purposes not listed in this medication guide.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not take rifapentine if you are allergic to rifapentine, rifabutin (Mycobutin), or rifampin (Rifadin, Rifater, Rimactane, Rifamate).

To make sure rifapentine is safe for you, tell your doctor if you have:

  • liver disease;

  • porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system);

  • HIV or AIDS;

  • if you have used rifampin or isoniazid in the past and they were not effective in treating TB; or

  • if you have been exposed to someone with TB that could not be treated with rifampin or isoniazid.

FDA pregnancy category C. It is not known whether rifapentine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

Rifapentine can make birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking rifapentine.

It is not known whether rifapentine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine. Rifapentine may cause a red-orange discoloration of breast milk.

Do not give this medicine to a child without medical advice.