Rifater
Generic name:isoniazid, pyrazinamide, and rifampin [ EYE-soe-NYE-a-zid, PIR-a-ZIN-a-mide, and-rif-AM-pin ]
Drug class:Antituberculosis combinations
What is Rifater?
Rifater are antibiotics that prevent tuberculous bacteria from multiplying in your body.
Rifater (Rifater) is a combination medicine used to treat tuberculosis (TB) in adults and children at least 15 years old.
Rifater may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you have severe liver disease, an attack of gout, if you take certain antiviral medicines, or if you have a history of fever, chills, and joint pain or stiffness caused by isoniazid.
Rifater can cause severe liver symptoms, especially in people who are 35 and older. Your liver function will need to be checked often.
Call your doctor at once if you have:nausea, vomiting, upper stomach pain, weakness, tiredness, loss of appetite, or yellowing of your skin or eyes.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
Avoid drinking alcohol.
Before taking this medicine
You should not use this medicine if you are allergic to isoniazid, pyrazinamide, or rifampin, or if you have:
severe liver disease;
an attack of gout; or
a history of fever, chills, and joint pain or stiffness caused by isoniazid.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with Rifater. Your doctor may change your treatment plan if you also use: atazanavir, darunavir, fosamprenavir, praziquantel, ritonavir, saquinavir, or tipranavir.
Serious and sometimes fatal liver problems may occur during treatment with this medicine or even months after you stop taking it. The risk of liver problems is highest in adults between the ages of 35 and 65.
Tell your doctor if you have ever had:
liver disease;
alcoholism (or if you drink alcoholic beverages every day);
gout;
diabetes; or
kidney disease.
