Rilonacept
Generic name: rilonacept [ ril-ON-a-sept ]
Brand name: Arcalyst
Dosage form: subcutaneous powder for injection (220 mg)
Drug class:Interleukin inhibitors
What is rilonacept?
Rilonacept is used to treat some of the symptoms of rare genetic conditions such as Familial Cold Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS).
FCAS and MWS are inflammatory disorders in which the body develops certain symptoms in response to cold, heat, stress, or tiredness. These symptoms often include rash, fever, and joint pain, and eye redness or discomfort. More serious symptoms may include deafness or kidney failure.
Rilonacept may treat or prevent the symptoms of Familial Cold Auto-inflammatory Syndrome (FCAS) or Muckle-Wells Syndrome (MWS) in adults and children at least 12 years old.
Rilonacept is also used to control symptoms of a condition called Deficiency of Interleukin-1 Receptor Antagonist (DIRA), in adults and children who weigh at least 22 pounds (10 kilograms). DIRA is a very rare genetic condition that causes a severe inflammatory reaction during the first days of life and can lead to organ failure throughout the body.
Rilonacept is not a cure for these inherited conditions.
Rilonacept is also used to reduce episodes of recurrent pericarditis (RP) in adults and children at least 12 years old. RP can cause pounding heartbeats, trouble breathing, and severe chest pain spreading to your back or neck.
Rilonacept may also be used for purposes not listed in this medication guide.
Warnings
Serious and sometimes fatal infections may occur during treatment with rilonacept. Call your doctor right away if you have signs of infection such as: fever, chills, sore throat, flu symptoms, or open sores on your body.
Before taking this medicine
You may not be able to use rilonacept if you have an active infection.
Tell your doctor if you have any signs of infection (fever, cough, flu symptoms, open sores), or if you have ever had:
an active or chronic infection, including HIV;
hepatitis B or C;
tuberculosis (or if anyone in your household has tuberculosis);
a weak immune system (caused by disease or by using certain medicine);
diabetes;
- MEDICAL DEPARTMENTS
CardiologyPediatricsDiabetes CarePre-natal CareUltrasound Echocardiogram