Rimabotulinumtoxinb (Intramuscular)
Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.
Postmarketing reports indicate that the effects of rimabotulinumtoxinB and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These may include asthenia, generalized muscle weakness, diplopia, blurred vision, ptosis, dysphagia, dysphonia, dysarthria, urinary incontinence, and breathing difficulties. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity but symptoms can also occur in adults treated for spasticity and other conditions, particularly in those patients who have underlying conditions that would predispose them to these symptoms. In unapproved uses, including spasticity in children and adults, and in approved indications, cases of spread of effect have occurred at doses comparable to those used to treat cervical dystonia and at lower doses .
Commonly used brand name(s)
In the U.S.
- Myobloc
Available Dosage Forms:
- Solution
Therapeutic Class: Cervical Agent
Pharmacologic Class: Neuromuscular Blocker, Non-Depolarizing
Uses for rimabotulinumtoxinb
RimabotulinumtoxinB injection is used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck). Rimabotulinumtoxinb is also used to treat chronic sialorrhea (drooling or excessive salivation) in adults. RimabotulinumtoxinB is a botulinum toxin B product. It works on the nervous system to relax the muscles.
RimabotulinumtoxinB is injected into the muscles that are affected. Depending on your condition, more than one treatment may be required.
Rimabotulinumtoxinb is available only with your doctor's prescription and will be given only by your doctor.
Before using rimabotulinumtoxinb
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For rimabotulinumtoxinb, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to rimabotulinumtoxinb or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of rimabotulinumtoxinB injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of rimabotulinumtoxinB injection in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines s..
