Generic name:amifampridine (oral route) [ am-i-FAM-pri-deen ]
Drug class:Cholinergic muscle stimulants
Medically reviewed by Drugs.com. Last updated on Mar 13, 2022.
Commonly used brand name(s)
In the U.S.
- Firdapse
- Ruzurgi
Available Dosage Forms:
- Tablet
Therapeutic Class: Central Nervous System Agent
Pharmacologic Class: Potassium Channel Blocker
Uses for Ruzurgi
Amifampridine is used to treat Lambert-Eaton myasthenic syndrome (LEMS), a rare autoimmune disease, wherein the immune system attacks the connection between the nerve and muscle (neuromuscular junction) and blocks the ability of the nerve cells to send signals to the muscle cells, leading to muscle weakness of the arms or legs.
This medicine is available only with your doctor's prescription.
Before using Ruzurgi
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of Firdapse® in children and Ruzurgi® in children younger than 6 years of age. Safety and efficacy have not been established.
Geriatric
No information is available on the relationship of age to the effects of Ruzurgi® in geriatric patients.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Firdapse® in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may r...
