Ryneze Liquid
Generic name: chlorpheniramine maleate and methscopolamine nitrate
Dosage form: liquid
Drug class:Upper respiratory combinations
Medically reviewed by Drugs.com. Last updated on Jun 21, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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DESCRIPTION:
Each teaspoonful (5 mL) for oral administration contains:
Chlorpheniramine Maleate ..... 4 mg
Scopolamine Methyl Nitrate ..... 1.25 mg
INACTIVE INGREDIENTS: Citric Acid, Grape flavor, Glycerin, Propylene Glycol, Purified Water, Sodium Citrate, Sodium
Saccharin, and Sorbitol.
RYNEZE® LIQUID contains ingredients from the following classes: antihistamine, and anticholinergic.
Chlorpheniramine Maleate is an antihistamine with the chemical name: 2-Pyridinepropanamine, γ-(4-chlorphenyl)-
N,N-dimethyl-, (Z)-2-butenedioate (1:1), and has the following chemical structure:
Scopolamine Methyl Nitrate is an anticholinergic belldonna alkaloid derivative with the chemical name:
[7(s)-(α,2β,4β,5α,7β,)]–7–(3–hydroxy–1-oxo – 2- Phenylpropoxy)-9, 9-dimethyl–3-oxa– 9-azoniatricyclo
[3.3.1.0 2,4] nonane nitrate.It has the following chemical structure:
CLINICAL PHARMACOLOGY:
Chlorpheniramine maleate competitively antagonizes most of the smooth muscle stimulating actions of histamine on the
H1 receptors of the GI tract, uterus, large blood vessels, and bronchial muscle. It also antagonizes the action of histamine
that results in increased capillary permeability and the formation of edema. Chlorpheniramine maleate is analkylamine-type antihistamine.
This group of antihistamines are among the most active histamine antagonists and are
generally effective in relatively low doses. They thereby p
