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Sacubitril and valsartan
  • Treatments
  • Heart Failure

Sacubitril and valsartan

Generic name: sacubitril and valsartan [ sak-UE-bi-tril-and-val-SAR-tan ]
Brand name: Entresto
Dosage form: oral tablet (24 mg-26 mg; 49 mg-51 mg; 97 mg-103 mg)
Drug class:Angiotensin receptor blockers and neprilysin inhibitors

Medically reviewed by Drugs.com on Apr 12, 2021. Written by Cerner Multum.

What is sacubitril and valsartan?

Sacubitril and valsartan is a combination medicine that is used in adults with chronic heart failure. sacubitril and valsartan helps lower the risk of needing to be hospitalized when symptoms get worse, and helps lower the risk of death from heart failure.

Sacubitril and valsartan is also used to treat heart failure in children who are at least 1 year old.

Sacubitril and valsartan is usually given together with other heart medications.

Sacubitril and valsartan may also be used for purposes not listed in this medication guide.

Warnings

Do not use if you are pregnant, and tell your doctor right away if you become pregnant.

If you have diabetes, do not use sacubitril and valsartan together with any medication that contains aliskiren (a blood pressure medicine).

Before taking this medicine

You should not use sacubitril and valsartan if you are allergic to sacubitril or valsartan (Diovan), or if you have ever had a severe allergic reaction to a blood pressure medication such as: