Selexipag (oral/injection)
Generic name: selexipag (oral/injection) [ se-LEX-i-pag ]
Brand names: Uptravi, Uptravi Titration Pack
Dosage forms: intravenous injection (1800 mcg); oral tablet (1000 mcg; 1200 mcg; 1400 mcg; 1600 mcg; 200 mcg; 200 mcg-800 mcg; 400 mcg; 600 mcg; 800 mcg)
Drug class:Agents for pulmonary hypertension
What is selexipag?
Selexipag is used to treat pulmonary arterial hypertension (PAH). Selexipag helps keep your condition from getting worse and helps lower your risk of needing to be hospitalized for PAH.
Selexipag may also be used for purposes not listed in this medication guide.
Warnings
Tell your doctor about all your other medicines. Some drugs should not be used with selexipag.
Before taking this medicine
You should not use selexipag if you are allergic to it.
Some drugs should not be used with selexipag. Your treatment plan may change if you also use:
Tell your doctor if you have ever had:
a condition called pulmonary veno-occlusive disease (narrowing of the veins that carry blood from the lungs to the heart); or
It is not known if selexipag will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Do not breastfeed.
How should I take selexipag?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Selexipag oral is taken by mouth.
You may take selexipag with or without food.
Swallow the tablet whole and do not crush, chew, or break it.
Selexipag injection is given in a vein by a healthcare provider if you are unable to take medicine by mouth.
Your condition may get worse if you stop using selexipag suddenly. Ask your doctor before stopping the medicine.
Store tablets at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 6 hours. Do not use two doses at one time.
If you miss doses for 3 or more days, call your doctor before taking another dose. You may need to restart the medicine at a lower dose than you took before.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
