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Semglee
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Semglee

Generic name:insulin glargineIN-su-lin-GLAR-gine ]
Drug class:Insulin

Medically reviewed by Judith Stewart, BPharm. Last updated on Mar 25, 2022.

What is Semglee?

Semglee is a man-made form of a hormone (insulin) that is produced in the body. Insulin is a hormone that works by lowering levels of glucose (sugar) in the blood. Insulin glargine is a long-acting insulin that starts to work several hours after injection and keeps working evenly for 24 hours.

Semglee is used to improve blood sugar control in patients with diabetes mellitus.

Semglee is for use in adults with type 1 or 2 diabetes and in children at least 6 years old with type 1 diabetes (not type 2).

  • Semglee is not for use to treat diabetic ketoacidosis.
  • It is not known if Semglee is safe and effective in children less than 6 years of age with type 1 diabetes.
  • It is not known if Semglee is safe and effective in children with type 2 diabetes.

For type 1 diabetes, Semglee is used together with a short-acting insulin given before meals.

Do not share your syringes with other people, even if the needle has been changed. You may give other people a serious infection, or get a serious infection from them.

Warnings

Do not use Semglee if you:

  • are having an episode of low blood sugar (hypoglycemia).
  • have an allergy to insulin glargine products or any of the ingredients in Semglee. See the end of this page for a complete list of ingredients.

Never share an injection pen, even if you changed the needle.

Before taking this medicine

You should not use Semglee if you are allergic to insulin, or if you are having an episode of hypoglycemia (low blood sugar) or diabetic ketoacidosis (call your doctor for treatment).

Semglee is not approved for use by anyone younger than 6 years old, and some brands are for use only in adults. Do not use Semglee to treat type 2 diabetes in a child of any age.

To make sure Semglee is safe for you, tell your doctor if you have:

  • liver or kidney disease; or

  • heart failure or other heart problems.

Tell your doctor if you also take pioglitazone or rosiglitazone (sometimes contained in combinations with glimepiride or metformin). Taking certain oral diabetes medicines while you are using insulin may increase your risk of serious heart problems.

Tell your doctor if you are pregnant or breastfeeding.

Follow your doctor's instructions about using Semglee if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy.

How shou...