Smoflipid
Dosage form: injection, emulsion
Drug class:Intravenous nutritional products
Medically reviewed by Drugs.com. Last updated on May 1, 2022.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- How Supplied/Storage and Handling
- Patient Counseling Information
1 INDICATIONS AND USAGE
Smoflipid is indicated in adult and pediatric patients, including term and preterm neonates, as a source of calories and essential fatty acids for parenteral nutrition (PN) when oral or enteral nutrition is not possible, insufficient, or contraindicated.
Smoflipid Dosage and Administration
2.1 Important Administration Instructions
- Smoflipid is prepared and administered by a healthcare provider in the inpatient setting. Patients and caregivers may prepare and administer Smoflipid for home use after appropriate training by a trained healthcare provider.
- Smoflipid is for central or peripheral intravenous infusion only.
- Smoflipid admixtures with osmolarity
- Greater than or equal to 900 mOsm/L must be infused through a central vein.
- Less than 900 mOsm/L may be administered either through a central or peripheral vein.
- Use a 1.2 micron in-line filter during administration.
- Use a dedicated infusion line without any connections. Do not connect multiple medications in series.
- To prevent air embolism, use a nonvented infusion set or close the vent on a vented set and fully evacuate residual gas in the bag prior to administration.
- Do not pressurize the flexible bag to increase flow rates, and if administration is controlled by a pumping device, turn off the pump before the bag runs dry.
- Do not use infusion sets and lines that contain di-2-ethylhexyl phthalate (DEHP), including infusion sets that contain polyvinyl chloride (PVC) components, because they contain DEHP as a plasticizer.
- Smoflipid can be infused concurrently into the same vein as dextrose-amino acid solutions (as part of PN) by a Y-connector located near the infusion site; flow rates of each solution should be controlled separately by infusion pumps.
- After connecting the infusion set, start infusion of Smoflipid immediately. Complete the infusion within 12 hours when using a Y-connector and w..