Smoflipid

Dosage form: injection, emulsion
Drug class:Intravenous nutritional products

Medically reviewed by Drugs.com. Last updated on May 1, 2022.

1 INDICATIONS AND USAGE

Smoflipid is indicated in adult and pediatric patients, including term and preterm neonates, as a source of calories and essential fatty acids for parenteral nutrition (PN) when oral or enteral nutrition is not possible, insufficient, or contraindicated.

Smoflipid Dosage and Administration

2.1 Important Administration Instructions

• Smoflipid is prepared and administered by a healthcare provider in the inpatient setting. Patients and caregivers may prepare and administer Smoflipid for home use after appropriate training by a trained healthcare provider.
• Smoflipid is for central or peripheral intravenous infusion only.
• Smoflipid admixtures with osmolarity
  • Greater than or equal to 900 mOsm/L must be infused through a central vein.
  • Less than 900 mOsm/L may be administered either through a central or peripheral vein.
• Use a 1.2 micron in-line filter during administration.
• Use a dedicated infusion line without any connections. Do not connect multiple medications in series.
• To prevent air embolism, use a nonvented infusion set or close the vent on a vented set and fully evacuate residual gas in the bag prior to administration.
• Do not pressurize the flexible bag to increase flow rates, and if administration is controlled by a pumping device, turn off the pump before the bag runs dry.
• Do not use infusion sets and lines that contain di-2-ethylhexyl phthalate (DEHP), including infusion sets that contain polyvinyl chloride (PVC) components, because they contain DEHP as a plasticizer.
• Smoflipid can be infused concurrently into the same vein as dextrose-amino acid solutions (as part of PN) by a Y-connector located near the infusion site; flow rates of each solution should be controlled separately by infusion pumps.
• After connecting the infusion set, start infusion of Smoflipid immediately. Complete the infusion within 12 hours when using a Y-connector and w..