Sodium Lactate

Dosage form: injection, solution, concentrate
Drug classes:Minerals and electrolytes, Urinary pH modifiers

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Injection, USP

Rx only

50 mEq (5 mEq/mL)

FOR ADDITIVE USE ONLY AFTER

DILUTION IN I.V. FLUIDS TO CORRECT

SERUM-BICARBONATE DEFICIT IN ACIDOSIS.

Plastic Vial

Sodium Lactate Description

Sodium Lactate Injection, USP 50 mEq (5 mEq/mL), is a sterile, nonpyrogenic, concentrated solution of Sodium Lactate in water for injection. The solution is administered after dilution by the intravenous route as an electrolyte replenisher and systemic alkalizer. It should not be administered undiluted. Each 10 mL vial contains Sodium Lactate, anhydrous 5.6 g (50 mEq each of Na+ and lactate anion). The solution contains no bacteriostat, antimicrobial agent or added buffer. Contains hydrochloric acid for pH adjustment. The osmolar concentration is 10 mOsmol/mL (calc.). When diluted with water for injection to make a 1/6 molar solution, the pH of Sodium Lactate injection is 6.5 (6.0 to 7.3).

Sodium Lactate, USP is chemically designated CH3CH(OH)COONa, a 60% aqueous solution miscible in water.

The semi-rigid vial is fabricated from a specially formulated polyolefin. It is a copolymer of ethylene and propylene. The safety of the plastic has been confirmed by tests in animals according to USP biological standards for plastic containers. The container requires no vapor barrier to maintain the proper drug concentration.

Sodium Lactate - Clinical Pharmacology

Lactate anion [CH3CH(OH)COO−] serves the important purpose of providing "raw material" for subsequent regeneration of bicarbonate (HCO3−) and thus acts as a source (alternate) of bicarbonate when normal production and utilization of lactic acid is not impaired as a ...