Stivarga

Generic name:regorafenib [ RE-goe-RAF-e-nib ]
Drug classes:Multikinase inhibitors, VEGF/VEGFR inhibitors

Medically reviewed by Sanjai Sinha, MD. Last updated on Apr 4, 2022.

What is Stivarga?

Stivarga is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Stivarga is used to treat colorectal cancer and liver cancer. It is also used to treat a rare type of tumor that can affect the esophagus, stomach, or intestines.

Stivarga is usually given after other cancer medications have been tried without success.

Warnings

Stivarga can cause serious or life-threatening liver problems. Call your doctor at once if you have nausea, vomiting, sleep problems, dark urine, or jaundice (yellowing of the skin or eyes).

You should not use Stivarga if past use has caused severe bleeding or severe liver problems.

Use birth control to prevent pregnancy, whether you are a man or a woman. Avoid pregnancy for at least 2 months after you stop using this medicine.

Before taking this medicine

To make sure Stivarga is safe for you, tell your doctor if you have:

• liver disease;

• high blood pressure;

• a bleeding or blood clotting disorder;

• heart disease, chest pain; or

• if you recently had surgery or plan to have surgery.

Both men and women using this medicine should use effective birth control to prevent pregnancy. Regorafenib can harm an unborn baby if the mother...