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Sudafed PE
  • Treatments
  • Nasal Congestion

Sudafed PE

Generic name:phenylephrine (oral) [ FEN-il-EFF-rin ]
Drug class:Decongestants

Medically reviewed by Philip Thornton, DipPharm. Last updated on Jun 23, 2021.

What is Sudafed PE?

Sudafed PE is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Sudafed PE is used to treat stuffy nose and sinus congestion caused by the common cold, hay fever, or other allergies.

Sudafed PE may also be used for purposes not listed in this medication guide.

Warnings

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not give Sudafed PE to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Ask a doctor or pharmacist before using any other cough or cold medicine. Phenylephrine or other decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains phenylephrine or a decongestant.

Before taking this medicine

Do not use Sudafed PE if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use Sudafed PE if you are allergic to phenylephrine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

How should I take Sudafed PE?

Use Sudafed PE exactly as directed on the label, or as prescribed by your doctor. Cold medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cold medicine to a child.

Measure liquid medicine (Children's Sudafed PE Nasal Decongestant) carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).