Sulfazine EC (Oral)

Generic name:sulfasalazine (oral route) [ sul-fa-SAL-a-zeen ]
Drug classes:5-aminosalicylates, Antirheumatics

Medically reviewed by Drugs.com. Last updated on Dec 23, 2021.

Commonly used brand name(s)

In the U.S.

• Azulfidine
• Azulfidine Entabs
• Sulfazine
• Sulfazine EC

In Canada

• alti-sulfaSALAzine
• Salazopyrin

Available Dosage Forms:

• Tablet
• Tablet, Enteric Coated

Therapeutic Class: Gastrointestinal Agent

Chemical Class: Salicylate, Non-Aspirin

Uses for Sulfazine EC

Sulfasalazine is used to treat and prevent acute attacks of mild to moderate ulcerative colitis. It works inside the bowels by helping to reduce the inflammation and other symptoms of the disease.

Sulfasalazine enteric-coated tablets are used to treat adults and children with rheumatoid arthritis in patients who have not been helped by or who cannot tolerate other medicines (eg, salicylates or NSAIDs) for rheumatoid arthritis.

This medicine is available only with your doctor's prescription.

Before using Sulfazine EC

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of sulfasalazine tablets and enteric-coated tablets to treat ulcerative colitis in children younger than 2 years of age. Safety and efficacy have not been established in children younger than 2 years of age.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of sulfasalazine enteric-coated tablets to treat juvenile rheumatoid arthritis in children. However, safety and efficacy have not been established in children younger than 6 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sulfasalazine in the elderly.

Breastfeeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an inter...