Tebentafusp-tebn (Intravenous)

Medically reviewed by Drugs.com. Last updated on May 27, 2022.

Commonly used brand name(s)

In the U.S.

• Kimmtrak

Available Dosage Forms:

• Solution

Therapeutic Class: Antineoplastic Agent

Uses for tebentafusp-tebn

Tebentafusp-tebn injection is used to treat uveal melanoma (eye cancer) that has spread or cannot be removed by surgery in patients who are HLA-A*02:01 positive. Your doctor will perform a test to check for the HLA-A*02:01 gene to make sure tebentafusp-tebn is right for you.

Tebentafusp-tebn is to be given only by or under the direct supervision of your doctor.

Before using tebentafusp-tebn

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tebentafusp-tebn, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to tebentafusp-tebn or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of tebentafusp-tebn injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tebentafusp-tebn injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of tebentafusp-tebn. Make sure you tell your doctor if you have any other medical problems, especially:

• Liver disease—Use with caution. May make this condition worse.

Proper use of tebentafusp-tebn

Medicines used to treat cancer are very strong and can have..