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Temozolomide
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  • Temozolomide (Oral)

Temozolomide (Oral)

Medically reviewed by Drugs.com. Last updated on Oct 24, 2021.

Commonly used brand name(s)

In the U.S.

  • Temodar

Available Dosage Forms:

  • Capsule

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Alkylating Agent

Chemical Class: Imidazole Carboxamide

Uses for temozolomide

Temozolomide is used to treat specific types of brain cancer (eg, glioblastoma multiforme, anaplastic astrocytoma) in patients whose tumors have returned or whose tumors have just been diagnosed. It belongs to the group of medicines known as antineoplastics (cancer medicines).

Temozolomide interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by temozolomide, other side effects may occur. Some of these may be serious and must be reported to your doctor. Some side effects may not occur for months or years after the medicine is used.

Before you begin treatment with temozolomide, you and your doctor should talk about the risks and benefits of temozolomide.

Temozolomide is available only with your doctor's prescription.

Before using temozolomide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For temozolomide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to temozolomide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of temozolomide in the pediatric population. Safety and efficacy have not been established. .

Geriatric

Although appropriate studies on the relationship of age to the effects of temozolomide have not been performed in the geriatric population, geriatric-specific problems are not expected to limit the usefulness of temozolomide in the elderly. However, elderly patients are more likely to have kidney, l...