Tenapanor (Oral)
Medically reviewed by Drugs.com. Last updated on May 1, 2022.
Tenapanor is contraindicated in patients less than 6 years of age; in nonclinical studies in young juvenile rats administration of tenapanor caused deaths presumed to be due to dehydration.Avoid use of tenapanor in patients 6 years to less than 12 years of age.The safety and effectiveness of tenapanor have not been established in patients less than 18 years of age .
Commonly used brand name(s)
In the U.S.
- Ibsrela
Available Dosage Forms:
- Tablet
Therapeutic Class: Colorectal Agent
Uses for tenapanor
Tenapanor is used to treat irritable bowel syndrome with constipation (IBS-C). Tenapanor is a sodium/hydrogen exchanger 3 (NHE3) inhibitor.
Tenapanor is available only with your doctor's prescription.
Before using tenapanor
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tenapanor, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to tenapanor or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Use of tenapanor is not recommended in children younger than 6 years of age. Avoid the use of tenapanor in children 6 to 17 years of age. Safety and efficacy have not been established in children.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tenapanor in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of tenapanor. Make sure you tell your doctor if you have any other medical problems, especially:
- Stomach or bowel blockage, known or suspected—Should not be used in patients with this condition.
Proper use of tenapanor
Take tenapanor exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your do..
