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Avalide
  • Treatments
  • High Blood Pressure

Avalide

Generic name:hydrochlorothiazide and irbesartanHYE-droe-KLOR-oh-THYE-a-zide-and-ir-be-SAR-tan ]
Drug class:Angiotensin II inhibitors with thiazides

Medically reviewed by Philip Thornton, DipPharm. Last updated on Mar 2, 2021.

What is Avalide?

Avalide tablets contain a combination of hydrochlorothiazide and irbesartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Irbesartan is an angiotensin II receptor antagonist. Irbesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Avalide is used to treat high blood pressure (hypertension).

Avalide may also be used for purposes not listed in this medication guide.

Warnings

Do not use Avalide if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.

You should not use this medicine if you are unable to urinate, or if you are allergic to sulfa drugs.

If you have diabetes, do not use Avalide together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

In rare cases, Avalide can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.

Before taking this medicine

You should not use Avalide if you are allergic to irbesartan or hydrochlorothiazide, or:

  • if you are unable to urinate; or

  • if you are aller...