Generic name: tolvaptan [ tol-VAP-tan ]
Brand names: Jynarque, Samsca, Jynarque 45 mg + 15 mg, Jynarque 60 mg + 30 mg, Jynarque 90 mg + 30 mg
Dosage form: oral tablet (15 mg; 30 mg; 45 mg-15 mg; 60 mg-30 mg; 90 mg-30 mg)
Drug class:Vasopressin antagonists
What is tolvaptan?
Jynarque is used to slow the decline in kidney function in adults who have autosomal dominant polycystic kidney disease.
Samsca is used to treat hyponatremia (low levels of sodium in your blood) in people with heart failure, and certain hormonal imbalances. Samsca improves urine flow without causing the body to lose too much sodium as you urinate.
Tolvaptan may also be used for purposes not listed in this medication guide.
Warnings
You will need frequent medical tests before and during treatment with tolvaptan.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.
You should not use tolvaptan if you are dehydrated or unable to urinate, or if you can't tell when you are thirsty.
You also should not use Jynarque if you have ever had liver problems (other than polycystic liver disease), or if your sodium blood level is too high or too low.
Samsca is given to treat low levels of sodium in your blood, but can be dangerous if this condition is reversed too quickly. Tell your caregivers at once if you have problems with speech or muscle control, trouble swallowin...
