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Tosymra
  • Treatments
  • Migraine

Tosymra

Generic name:sumatriptan
Dosage form: nasal spray
Drug class:Antimigraine agents

Medically reviewed by Melisa Puckey, BPharm. Last updated on Apr 5, 2022.

What is Tosymra?

Tosymra is a nasal spray medicine used to treat acute migraine headaches with or without aura in adults.
It is not used to treat other types of headaches such as hemiplegic (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines.

Tosymra is not used to prevent or decrease the number of migraines you have. Tosymra is not used to treat cluster headaches. It is not known if it is safe and effective in children under 18 years of age.

Tosymra is a serotonin (5-HT1B/1D) receptor agonist (triptan)

Important information

Tosymra can cause serious side effects, including:

Heart attack and other heart problems. Heart problems may lead to death.

Stop taking Tosymra and get emergency medical help right away if you have any of the following symptoms of a heart attack:

  • discomfort in the center of your chest that lasts for more than a few minutes, or that goes away and comes back
  • severe tightness, pain, pressure, or heaviness in your chest, throat, neck, or jaw
  • pain or discomfort in your arms, back, neck, jaw, or stomach
  • shortness of breath with or without chest discomfort
  • breaking out in a cold sweat, nausea or vomiting
  • feeling lightheaded

Tosymra is not for people with risk factors for heart disease unless a heart exam is done and shows no problem. You have a higher risk for heart disease if you:

  • have high blood pressure
  • have high cholesterol levels
  • smoke
  • are overweight
  • have diabetes
  • have a family history of heart disease

Who should not use Tosymra?

Do not take Tosymra if you have:

  • heart problems or a history of heart problems
  • narrowing of blood vessels to your legs, arms, stomac.