Tricitrasol
Generic name: trisodium citrate dihydrate
Dosage form: extracorporeal solution
Drug class:Urinary pH modifiers
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
ANTICOAGULANT SODIUM CITRATE CONCENTRATE – 46.7% Trisodium Citrate
PN 6030, 30 mL
NDC 23731-6030-3
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Tricitrasol Description
Tricitrasol® Anticoagulant Sodium Citrate Concentrate, 46.7% Trisodium Citrate, is a sterile, non-pyrogenic solution of Trisodium Citrate (Dihydrate), USP.
Each 30 mL of concentrate contains:
Trisodium Citrate, dihydrate, USP | 14.0 grams |
Water for Injection, USP | q.s. |
pH adjusted with Citric Acid
pH: 6.3 – 6.6
Single patient use only, on a single occasion.
Tricitrasol - Clinical Pharmacology
A sodium citrate solution acts as an anticoagulant by the action of the citrate ion chelating free ionized calcium; thus, the calcium ion is unavailable to the coagulation system 1.
Indications and Usage for Tricitrasol
Tricitrasol® Anticoagulant Sodium Citrate Concentrate, 46.7% Trisodium Citrate, is an anticoagulant used in granulocytapheresis procedures (granulocyte collection by apheresis). Just prior to performing granulocytapheresis, aseptically add 30 mL of Tricitrasol® to 500 mL of the 6% solution of Hydroxyethyl Starch (HES), e.g. Hespan ® 2-8. Agitate the resultant solution for 1 minute to assure a uniform concentration of anticoagulant. The resultant solution of Tricitrasol® and 6% solution of HES conta.