Triderma Cream
Generic name:hydroquinone, tretinoin, fluocinolone acetonide
Dosage form: cream
Drug class:Topical depigmenting agents
Medically reviewed by Drugs.com. Last updated on Mar 1, 2022.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. Read further information about unapproved drugs.
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Composition
Each 1 g contains: Hydroquinone 40 mg, Tretinoin 0.5 mg and Fluocinolone Acetonide 0.1 mg.
Excipients: Emulsifying Wax, Cetyl Alcohol, Glycerin, Cetostaeryl Alcohol, Glycerol Monostearate, Stearic Acid, White Soft Paraffin, Sodium Metabisulfite, Methylparaben, Citric Acid, Butylated Hydroxyanisole, Propylparaben, and Purified Water.
Properties
Fluocinolone acetonide is a synthetic fluorinated corticosteroid for topical dermatological use and is classified therapeutically as an anti-inflammatory. It is a white crystalline powder that is odorless and stable in light. Hydroquinone is classified therapeutically as a de-pigmenting agent. It is prepared from the reduction of p-benzoquinone with sodium bisulfite. It occurs as fine white needles that darken on exposure to air. Tretinoin is all-trans-retinoic acid formed from the oxidation of the aldehyde group of retinene to a carboxyl group. It occurs as yellow to light-orange crystals or crystalline powder with a characteristic odor of ensilage. It is highly reactive to light and moisture. Tretinoin is classified therapeutically as a keratolytic.
Indications
Triderma is indicated for the short-term intermittent treatment of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens.
Contraindications
Triderma is contraindicated in individuals with a history of hypersensitivity, allergy, or intolerance to this product or any of its components.
Precautions
Triderma contains hydroquinone and tretinoin that may cause mild to moderate irritation. Local irritation, such as skin reddening, peeli..
