Trifarotene

Class: Skin and Mucous Membrane Agents, Miscellaneous
Chemical Name: 4-[3-(3-tert-butyl-4-pyrrolidin-1-ylphenyl)-4-(2-hydroxyethoxy)phenyl]benzoic acid
Molecular Formula: C₂₉H₃₃NO₄
CAS Number: 895542-09-3
Brands: Aklief

Medically reviewed by Drugs.com on Oct 18, 2021. Written by ASHP.

Introduction

Trifarotene is a skin or mucous membrane agent.

Uses for Trifarotene

Trifarotene has the following uses:

Trifarotene cream is a retinoid indicated for the topical treatment of acne vulgaris in patients 9 years of age and older.

Trifarotene Dosage and Administration

General

Trifarotene is available in the following dosage form(s) and strength(s):

Cream: 0.005% trifarotene.

Dosage

It isessentialthat the manufacturer's labeling be consulted for more detailed information on dosage and administration of this drug. Dosage summary:

Pediatric Patients

Dosage and Administration

• For topical use only. Not for oral, ophthalmic, or intravaginal use.

• Apply a thin layer of trifarotene cream to the affected areas once daily, in the evening, on clean and dry skin. Avoid contact with the eyes, lips, paranasal creases, mucous membranes.

• One pump actuation should be enough to cover the face (i.e., forehead, cheeks, nose, and chin).

• Two actuations of the pump should be enough to cover the upper trunk (i.e., reachable upper back, shoulders and chest). One additional pump actuation may be used for middle and lower back if acne is present.

• The use of a moisturizer is recommended as frequently as needed from the initiation of treatment.

Adults

Dosage and Administration

• For topical use only. Not for oral, ophthalmic or intravaginal use.

• Apply a thin layer of trifarotene cream to the affected areas once daily, in the evening, on clean and dry skin. Avoid contact with the eyes, lips, paranasal creases, and mucous membranes.

• One pump actuation should be enough to cover the face (i.e., forehead, cheeks, nose, and chin).

• Two actuations of the pump should be enough to cover the upper trunk (i.e., reachable upper back, shoulders and chest). One additional pump actuation may be used for middle and lower back if acne is present.

• The use of a moisturizer is recommended as frequently as needed from the initiation of treatment.

Cautions for Trifarotene

Contraindications

None.

Warnings/Precautions

Skin Irritation<...