Trifarotene (Topical application)

Medically reviewed by Drugs.com. Last updated on Feb 18, 2022.

Commonly used brand name(s)

In the U.S.

• Aklief

Available Dosage Forms:

• Cream

Therapeutic Class: Antiacne

Chemical Class: Retinoid

Uses for trifarotene

Trifarotene cream is used to treat acne. Trifarotene works to help clear acne by keeping the skin pores (tiny openings on the skin) clean.

Trifarotene is available only with your doctor's prescription.

Before using trifarotene

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For trifarotene, the following should be considered:

Allergies

The dose of trifarotene will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of trifarotene. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of trifarotene cream in children 9 years of age and older. However, safety and efficacy of trifarotene cream have not been established in children younger than 9 years of age.

Geriatric

Appropriate studies on the relationship of age to the effects of trifarotene cream have not been performed in the geriatric population.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of trifarotene. Make sure you tell your doctor if you have any other medical problems, especially:

• Eczema (skin problem) or
• Sunburn—May cause skin irritation and should not be used in patients with these conditions.

Proper use of trifarotene

It is very important that you use trifarotene only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do ...