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Trijardy XR
  • Treatments
  • Diabetes
  • Type 2

Trijardy XR

Generic name:empagliflozin, linagliptin, and metforminEM-pa-gli-FLOE-zin, LIN-a-GLIP-tin, and-met-FOR-min ]
Dosage form: oral tablet, extended release (10 mg-5 mg-1000 mg; 12.5 mg-2.5 mg-1000 mg; 25 mg-5 mg-1000 mg; 5 mg-2.5 mg-1000 mg)
Drug class:Antidiabetic combinations

Medically reviewed by Judith Stewart, BPharm. Last updated on Nov 8, 2021.

What is Trijardy XR?

Trijardy XR tablets contains a comination of empagliflozin, linagliptin, and metformin. Empagliflozin, linagliptin, and metformin are all oral diabetes medicines that help control blood sugar levels.

Trijardy XR is a prescription medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

Trijardy XR is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.

Trijardy XR is not for treating type 1 diabetes.

Warnings

You should not use Trijardy XR if you have severe kidney disease (or if you are on dialysis) or diabetic ketoacidosis, or if you have ever had a severe allergic reaction to metformin, empagliflozin or linagliptin.

Call your doctor at once if you have signs of a serious side effect, such as severe pain in your upper stomach spreading to your back, vomiting, fast heart rate, dizziness, feeling very thirsty or hot, decreased urination, heavy sweating, or hot and dry skin.

Tell your doctor if you are sick with vomiting or diarrhea, or if you eat or drink less than usual.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

In rare cases, Trijardy XR can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

Before taking this medicine

You should not use Trijardy XR if you are allergic to empagliflozin, linagliptin, or metformin, or if you have:

  • severe kidney disease (or if you are on dialysis);

  • a history of severe allergic or skin reaction after taking linagliptin; or

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