Generic name:ravulizumab [ RAV-ue-LIZ-ue-mab ]
Drug class:Selective immunosuppressants
What is Ultomiris?
Ultomiris is a monoclonal antibody. Monoclonal antibodies are man-made antibodies that fight antigens (harmful substances) in the body.
Ultomiris injection is used to treat paroxysmal nocturnal hemoglobinuria (PNH) in adults and children who are at least 1 month old.
PNH is a rare genetic disorder in which defective red blood cells break down prematurely and leak hemoglobin into your blood. Hemoglobin is the iron-rich protein that gives blood its red color. When hemoglobin passes into your urine, it can appear dark or tea-colored (especially in the morning or after sleep, when the urine is most concentrated).
Ultomiris is used to treat a rare chronic blood disease called hemolytic uremic syndrome (aHUS) in adults and children who are at least 1 month old. This medicine is not for use in treating HUS that is related to Shiga toxin E. coli.
Ultomiris is also used to treat adults with generalized myasthenia gravis (gMG) who are anti-acetylcholine receptor (AChR) antibody positive.
Ultomiris is available only under a special program. You must be registered in the program and understand the risks and benefits of this medicine.
Warnings
Ultomiris affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, flu-like symptoms, muscle pain, headache, confusion, neck or back stiffness, vomiting, rash, or your eyes are more sensitive to light.
You will need to receive certain vac...
