Vasocidin
Generic name:prednisolone sodium phosphate and sulfacetamide sodium
Dosage form: ophthalmic solution
Drug class:Ophthalmic steroids with anti-infectives
Medically reviewed by Drugs.com. Last updated on Feb 21, 2022.
Vasocidin®
SULFACETAMIDE SODIUM AND PREDNISOLONE SODIUM PHOSPHATE
OPHTHALMIC SOLUTION, USP
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The Vasocidin brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
DESCRIPTION
Vasocidin is a sterile topical ophthalmic solution combining an anti-infective and an adrenocortical steroid having the following composition:
Sulfacetamide Sodium 100 mg/mL
(bacteriostatic antibacterial)
Prednisolone Sodium Phosphate 2.5mg/mL
(equivalent to Prednisolone Phosphate 2.3 mg/mL)
(adrenocortical steroid/anti-inflammatory)
In a solution containing edetate disodium, poloxamer 407, boric acid, purified water, preserved with thimerosal 0.1 mg/mL. Hydrochloric acid and/or sodium hydroxide added to adjust pH.
The chemical name for sulfacetamide sodium is Acetamide, N-[(4-aminophenyl) sulfonyl]-, monosodium salt, monohydrate.
The chemical name for prednisolone sodium phosphate is 11ß, 17, 21-trihydroxypregna-1,4-diene-3,20-dione, 21-(disodium phosphate).
They have the following chemical structures:
CLINICAL PHARMACOLOGY
Corticosteroids suppress the inflammatory response to a variety of agents and they probably delay or slow healing. Since corticosteroids may inhibit the body's defense mechanism against infection, a concomitant antimicrobial drug may be used when this inhibition is considered to be clinically significant in a particular...
