Vasocon
Generic name:naphazoline hydrochloride
Dosage form: Vasocon
Drug class:Ophthalmic antihistamines and decongestants
Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.
VASOCON REGULAR
NAPHAZOLINE HYDROCHLORIDE OPHTHALMIC SOLUTION USP, 0.1%
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Vasocon Description
Naphazoline HCl, an ocular Vasoconstrictor, is an imidazoline derivative sympathomimetic amine. The active ingredient is represented by the structural formula:
Chemical Name:
2-(1-naphthylmethyl)-2-imidazoline monohydrochloride
VASOCON REGULAR ophthalmic solution is a sterile solution containing 1 mg/mL naphazoline hydrochloride in an isotonic solution containing polyethylene glycol 8000, sodium chloride, polyvinyl alcohol, edetate disodium and purified water; preserved with benzalkonium chloride. Hydrochloric acid and/or sodium hydroxide added to adjust pH. It has a pH of 5.5 to 7.0.
Vasocon - Clinical Pharmacology
Naphazoline constricts the vascular system of the conjunctiva. It is presumed that this effect is due to direct stimulation action of the drug upon the alpha adrenergic receptors in the arterioles of the conjunctiva resulting in decreased conjunctival congestion. Naphalozine belongs to the imidazoline class of sympathomimetics.
Indications and Usage for Vasocon
VASOCON REGULAR is indicated for use as a topical ocular Vasoconstrictor.
Contraindications
Contraindicated in the presence of an anatomically narrow angle or in narrow angle glaucoma or in persons who have shown hypersensitivity to any component of this preparation.
Warnings
Patients under therapy with MAO inhibitors may experience a severe hypertensive crisis if given a sympathomimetic drug. Use in children, especially infants, may result in CNS depression leading to coma and marked reduction in body temperature.
Precautions
General
Use with caution in the presence of hypertension, cardiovascular abnormalities, hyperglycemia (diabetes), hyperthyroidism, ocular infection or injury and when other medications are being used.
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