Vincristine liposome

Generic name: vincristine liposome [ vin-KRIS-teen-LYE-poe-some ]
Brand name: Marqibo
Dosage form: intravenous kit (5 mg/31 mL)
Drug class:Mitotic inhibitors

Medically reviewed by Drugs.com on Mar 3, 2022. Written by Cerner Multum.

What is vincristine liposome?

Vincristine liposome is used to treat a type of blood cancer called Philadelphia chromosome negative acute lymphoblastic leukemia (ALL).

Vincristine liposome is given after at least two other cancer treatments did not work or have stopped working.

Vincristine liposome may also be used for purposes not listed in this medication guide.

Warnings

You should not use vincristine liposome if you have Charcot-Marie-Tooth syndrome or other conditions that cause damage to myelin (protective covering of the nerves in your brain and spinal cord).

Before taking this medicine

You should not use vincristine liposome if you are allergic to it, or if you have Charcot-Marie-Tooth syndrome or other conditions that cause damage to myelin (protective covering of the nerves in your brain and spinal cord).

Tell your doctor if you have ever had:

• liver disease;

• a nerve-muscle disorder such as myasthenia gravis, ALS (Lou Gehrig's disease), multiple sclerosis, or muscular dystrophy;

• a bowel obstruction called paralytic ileus; or

• peripheral vascular disease such as Raynaud's syndrome.

Vincristine liposome may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

You should not breastfeed while using vincristine liposome. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby. Follow your doctor's instructions about when you can start breastfeeding again after your treatment ends.

How is vincristine liposome given?

Vincristine liposome is given as an infusion into a vein, usually once a week. A healthcare provider will give you this injection.

vincristine liposome must be given slowly, and the infusion can take at least 1 hour to complete.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when vincristine liposome is injected.

Vincristine liposome can cause severe