Vincristine liposome (Intravenous)
Medically reviewed by Drugs.com. Last updated on May 6, 2022.
VinCRIStine sulfate liposome is for IV use only and is fatal if given by other routes. Death has occurred with intrathecal use. VinCRIStine sulfate liposome injection has different dosage recommendations than vinCRIStine sulfate injection. Verify drug name and dose before preparation and administration to avoid overdosage .
Commonly used brand name(s)
In the U.S.
- Marqibo
Available Dosage Forms:
- Suspension
Pharmacologic Class: Mitotic Inhibitor
Uses for vincristine liposome
Vincristine liposome injection is used to treat Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL) that has worsen or come back or in patients who have received at least 2 previous cancer treatments that did not work well.
Vincristine liposome is an antineoplastic agent (cancer medicine). It interferes with the growth of cancer cells, which are eventually destroyed by the body.
Vincristine liposome is to be given only by or under the direct supervision of your doctor.
Before using vincristine liposome
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For vincristine liposome, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to vincristine liposome or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of vincristine liposome injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of vincristine liposome injection in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution for patients receiving vincristine liposome.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving vincristine liposome, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using vincristine liposome with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
- Boceprevir
