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Vinorelbine, Concentrate
  • Professionals
  • FDA PI

Vinorelbine, Concentrate

Generic name: vinorelbine tartrate
Dosage form: injection, solution, concentrate
Drug class:Mitotic inhibitors

Medically reviewed by Drugs.com. Last updated on Aug 23, 2021.

WARNING: MYELOSUPPRESSION
Severe myelosuppression resulting in serious infection, septic shock, hospitalization and death may occur [see Warnings and Precautions (5.1)].
Decrease the dose or withhold vinorelbine in accord with recommended dose modifications [see Dosage and Administration (2.2)].

Indications and Usage for Vinorelbine, Concentrate

Vinorelbine injection USP is indicated:

In combination with cisplatin for first-line treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC)
As a single agent, for the treatment of patients with metastatic NSCLC

Vinorelbine, Concentrate Dosage and Administration

Recommended Dose

In Combination with Cisplatin 100 mg/m2

The recommended dose of vinorelbine injection is 25 mg/m2 administered as an intravenous injection or infusion over 6 to 10 minutes on days 1, 8, 15 and 21 of a 28 day cycle in combination with cisplatin 100 mg/m2 on day 1 only of each 28 day cycle.

In Combination with Cisplatin 120 mg/m2

The recommended dose of vinorelbine injec...