Viramune O/S (Oral)
Generic name: nevirapine (oral route) [ ne-VIR-a-peen ]
Drug class:NNRTIs
Medically reviewed by Drugs.com. Last updated on Mar 31, 2022.
Severe, life-threatening, in some cases fatal, hepatotoxicity and skin reactions (eg, Stevens-Johnson syndrome, toxic epidermal necrolysis, and hypersensitivity reactions characterized by rash, constitutional findings, and organ dysfunction) have been reported. Women, including pregnant women, or patients with higher CD4+ cell counts are at higher risk of hepatotoxicity. Permanently discontinue nevirapine following severe hepatic, skin, or hypersensitivity reactions. Check transaminase levels immediately for all patients who develop a rash during the first 18 weeks of treatment. Monitor patients intensively during the first 18 weeks of therapy with nevirapine to detect potentially life-threatening hepatotoxicity or skin reactions. Extra vigilance is warranted during the first 6 weeks of therapy, which is the period of greatest risk for adverse events. Strictly follow the 14-day lead-in period with immediate-release nevirapine 200 mg daily dosing .
Commonly used brand name(s)
In the U.S.
- Viramune
- Viramune O/S
- Viramune XR
Available Dosage Forms:
- Tablet, Extended Release
- Tablet
- Suspension
Therapeutic Class: Antiretroviral Agent
Pharmacologic Class: Non-Nucleoside Reverse Transcriptase Inhibitor
Uses for Viramune O/S
Nevirapine is used in combination with other medicines for the treatment of the infection caused by human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS).
Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It works by lowering the amount of HIV in the blood.
Nevirapine will not cure HIV infection or AIDS, however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems that usually result from AIDS or HIV disease. Nevirapine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have some of the problems usually related to AIDS or HIV disease.
This medicine is available only with your doctor's prescription.
Before using Viramune O/S
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of nevirapine suspensionor tablets in children. However, safety and efficacy have not been established in infants younger than 15 days of age.
Appropriate studies perf..
