Xcopri

Generic name:cenobamate
Dosage form: Tablets
Drug class:Carbamate anticonvulsants
Approval date:  November 21, 2019
Company: SK Life Science, Inc.
Treatment for: Partial-Onset Seizures

Medically reviewed by Judith Stewart, BPharm. Last updated on Mar 8, 2022.

What is Xcopri?

Xcopri is a prescription medicine used to treat partial-onset seizures in adults.

It is not known if Xcopri is safe and effective in children.

Warnings

What is the most important information I should know about Xcopri?

Xcopri can cause serious side effects, including:

1. Serious or life threatening allergic reactions which may affect organs and other parts of your body like the liver or blood cells. You may or may not have a rash with these types of reactions.
   Call your healthcare provider right away and go to the nearest emergency room if you have any of the following:
   • swelling of your face, eyes, lips, or tongue
   • trouble swallowing or breathing
   • a skin rash
   • hives
   • fever, swollen glands, or sore throat that does not go away or comes and goes
   • painful sores in the mouth or around your eyes
   • yellowing of your skin or eyes
   • unusual bruising or bleeding
   • severe fatigue or weakness
   • severe muscle pain
   • frequent infections that do not go away
     These symptoms may be the first signs of a serious reaction. A healthcare provider should examine you to decide if you should continue treatment.
2. Like other antiepileptic drugs, Xcopri may cause suicidal thoughts or actions in a very small number of people, about 1 in 500.
   Call a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:
   • thoughts about suicide or dying
   • attempts to commit suicide
   • new or worse depression
   • new or worse anxiety
   • feeling agitated or restless
   • panic attacks
   • trouble sleeping (insomnia)
   • new or worse irritability
   • acting aggressive, being angry, or violent
   • acting on dangerous impulses
   • an extreme increase in activity and talking (mania)
   • other unusual changes in behavior or mood
   • Suicidal thoughts or actions may be caused by things other than medicines. If you have suicidal thoughts or actions, your healthcare provider may check for other causes.
     
     How can I watch for early symptoms of suicidal thoughts and actions?
   • Pay attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings.
   • Keep all follow-up visits with your healthcare provider as scheduled.
     Call your healthcare provider between visits as needed, especially if you are worried about symptoms.
3. Do not stop taking Xcopri without first talking to your healthcare provider.
   • Stopping Xcopri suddenly can cause serious problems.
   • Stopping a seizure medicine suddenly can cause seizures that will not stop (status epilepticus).
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