Xenleta (oral/injection)

Generic name:lefamulin (oral/injection) [ le-FAM-ue-lin ]
Drug class:Miscellaneous antibiotics

Medically reviewed by Drugs.com on Oct 29, 2021. Written by Cerner Multum.

What is Xenleta?

Xenleta is used to treat certain types of pneumonia in adults.

Xenleta may also be used for purposes not listed in this medication guide.

Warnings

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

You should not use Xenleta if you are allergic to it.

Many drugs can interact and cause dangerous effects. Some drugs should not be used together with Xenleta. Your doctor may change your treatment plan if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Tell your doctor if you have ever had:

• a heart rhythm disorder (especially if you take medication to treat it);

• long QT syndrome;

• liver disease; or

• kidney disease (or if you are on dialysis).

You may need to have a negative pregnancy test before starting this treatment.

Xenleta may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using Xenleta and for at least 2 days after your last dose. Tell your doctor if you become pregnant.

You should not breastfeed within 2 days after using Xenleta. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

How should I take Xenleta?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Xenleta oral is taken by mouth.

Take Xenleta oral on an empty stomach, at least 1 hour before or 2 hours after a meal.

Take Xenleta oral with a full glass (6 to 8 ounces) of water. Swallow the tablet whole and do not crush, chew, or break it.

Xenleta injection is given as an infusion into a vein. A healthcare provider will give your first dose and may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all...