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Zelboraf
  • Treatments
  • Melanoma
  • Metastatic

Zelboraf

Generic name:vemurafenibVEM-ue-RAF-e-nib ]
Drug class:Multikinase inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 21, 2022.

What is Zelboraf?

Zelboraf is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Zelboraf is used to treat melanoma (skin cancer) that has spread to other parts of the body or cannot be removed by surgery.

Zelboraf is also used to treat Erdheim-Chester Disease (a rare blood cancer).

Zelboraf is used only if your cancer has a specific genetic marker (an abnormal "BRAF" gene). Your doctor will test you for this gene.

Warnings

Zelboraf is used to treat melanoma, but this medicine can increase your risk of developing other types of skin cancer. Report any new or worsening skin lesions to your doctor right away.

Many drugs can interact with vemurafenib. Tell your doctor about all your current medicines and any you start or stop using

Before taking this medicine

You should not use Zelboraf if you are allergic to vemurafenib.

To make sure Zelboraf is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;

  • heart problems;

  • long QT syndrome (in you or a family member); or

  • an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood).

Tell your doctor about all radiation treatments you are scheduled to receive, or have received in the past.

Using Zelboraf may increase your risk of developing other types of skin cancer. Report any new or worsening skin lesions to your doctor right away.

Vemurafenib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using this medicine, and fo...