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Zestril
  • Treatments
  • High Blood Pressure

Zestril

Generic name:lisinoprillyse-IN-oh-pril ]
Brand names: Prinivil, Qbrelis, Zestril
Drug class:Angiotensin Converting Enzyme Inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on Nov 19, 2021.

What is Zestril?

Zestril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Zestril is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old.

Zestril is also used to treat congestive heart failure in adults, or to improve survival after a heart attack.

Warnings

Do not use Zestril if you are pregnant. It could harm the unborn baby. Stop using this medicine and tell your doctor right away if you become pregnant.

You should not use Zestril if you have ever had angioedema. Do not take this medicine within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use Zestril together with any medication that contains aliskiren (such as Tekturna or Tekamlo).

You may also need to avoid taking Zestril with aliskiren if you have kidney disease.

Before taking this medicine

You should not use Zestril if you are allergic to lisinopril, or if you:

  • have a history of angioedema;

  • recently took a heart medicine called sacubitril; or

  • are allergic to any other ACE inhibitor, such as benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril.

Do not take Zestril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use Zestril together with any medication that contains al...