Medically reviewed by Drugs.com. Last updated on Feb 9, 2022.
Zidovudine has been associated with hematologic toxicity, including neutropenia and severe anemia, particularly in patients with advanced HIV disease. Prolonged use of zidovudine has been associated with symptomatic myopathy. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported. Suspend treatment if clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicity occur .
Commonly used brand name(s)
In the U.S.
- Retrovir
Available Dosage Forms:
- Solution
Therapeutic Class: Antiretroviral Agent
Pharmacologic Class: Nucleoside Reverse Transcriptase Inhibitor
Uses for zidovudine
Zidovudine (also known as AZT) injection is used together with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Zidovudine injection is used to slow the progression of disease in patients infected with HIV who have advanced symptoms, early symptoms, or no symptoms at all. Zidovudine is also used to help prevent pregnant women who have HIV from passing the virus to their babies during pregnancy and at birth.
Zidovudine injection will not cure or prevent HIV infection or AIDS, however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems that usually result from AIDS or HIV disease. Zidovudine injection will not keep you from spreading HIV to other people. People who receive zidovudine may continue to have the problems usually related to AIDS or HIV disease.
Zidovudine is to be given only by or under the direct supervision of your doctor.
Before using zidovudine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For zidovudine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to zidovudine or any other medicines...
