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Zilretta
  • Treatments
  • Osteoarthritis

Zilretta

Generic name:triamcinolone acetonide
Dosage form: extended-release injectable suspension
Drug class:Glucocorticoids

Medically reviewed by Judith Stewart, BPharm. Last updated on May 11, 2022.

What is Zilretta?

Zilretta is an extended-release corticosteroid approved to manage osteoarthritis knee pain.

The benefits and risks of repeat injections have not been demonstrated.

Who should not receive Zilretta?

You should not receive a Zilretta injection if you are allergic to corticosteroids, triamcinolone acetonide, or any other ingredient in Zilretta.

What possible side effects of corticosteroids could occur with Zilretta?

  • Rare serious allergic reactions
  • Effects in the injected knee such as infection (with pain, swelling and restricted motion) or joint damage
  • Increased chance of getting an infection, and a decreased ability to fight an infection
  • Effects on hormone production. These effects can be reversible
  • Elevated blood pressure, sodium and water retention, and potassium loss
  • Intestinal perforation if you have certain gastrointestinal disorders
  • Weakening of bones
  • Changes in behavior or mood disturbances
  • Increased pressure inside the eye

Zilretta side effects

In multiple clinical trials, the most common side effects seen in people taking Zilretta were joint pain, headache, joint swelling, back pain, sore throat and runny nose, upper respiratory tract infection, and bruising.

What should you tell your doctor BEFORE receiving a Zilretta i..