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Zinbryta
  • Treatments
  • Multiple Sclerosis

Zinbryta

Generic name:daclizumabdah-KLIH-zyoo-mab ]
Drug class:Interleukin inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on Feb 28, 2022.

What is Zinbryta?

Zinbryta is a monoclonal antibody that affects the actions of the body's immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

Zinbryta is used to treat relapsing forms of multiple sclerosis.

Zinbryta is usually given when other medicines have not been effective.

Zinbryta is available only from a certified pharmacy under a special program. You must be registered in the program and understand the risks and benefits of taking this medicine.

Warnings

You should not use Zinbryta if you have liver disease or if you have ever had autoimmune hepatitis.

Zinbryta can cause serious or fatal liver problems. Call your doctor right away if you have symptoms such as nausea, vomiting, upper stomach pain, tiredness, loss of appetite, dark urine, or jaundice (yellowing of the skin or eyes).

You will need frequent blood tests to check your liver function during treatment and after you stop using this medicine. Future doses may be delayed based on the results of these tests.

Zinbryta may also increase your risk of certain infections or immune system problems. Call your doctor if you have a skin rash, fever, swollen glands, diarrhea, stomach pain, blood in your stools, or any other new or unusual symptoms.

Before taking this medicine

You should not use Zinbryta if you are allergic to daclizumab, or if you have ever had:

  • liver disease; or

  • a history of autoimmune hepatitis.

To make sure Zinbryta is safe for you, tell your doctor if you have:

  • an active infection, including tuberculosis;

  • liver problems, including hepatitis B or C;

  • skin problems such as eczema or psoriasis;

  • depression; or

  • if you are scheduled to receive any vaccines.

It is not known whether Zinbryta will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether daclizumab passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding a baby.

Zinbryta is not approved for use by anyone younger than 18 years old.

How should I use Zinbryta?

Use Zinbryta exactly as it was prescribed for you. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Zinbryta is injected under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.

Zinbryta is usually ...