BAT Botulism Antitoxin
Generic name: botulism antitoxin heptavalent
Dosage form: injection, solution
Drug class:Antitoxins and antivenins
Medically reviewed by Drugs.com. Last updated on Oct 1, 2020.
On This Page
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- References
- How Supplied/Storage and Handling
- Patient Counseling Information
Indications and Usage for BAT Botulism Antitoxin
BAT [Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G) – (Equine)] is a mixture of immune globulin fragments indicated for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes A, B, C, D, E, F, or G in adults and pediatric patients.
The effectiveness of BAT is based on efficacy studies conducted in animal models of botulism.
BAT Botulism Antitoxin Dosage and Administration
BAT is for intravenous use only.
Dosage and Administration
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- Each vial of BAT contains a minimum potency for serotypes A, B, C, D, E, F, and G antitoxin [see Dosage Forms and Strengths (3 DOSAGE FORMS AND STRENGTHS
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- For adult, pediatric, and infant patient groups, administer a dose of BAT according to Table 1. For details on pediatric dosing by body weight see Table 2.
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- Administer all BAT doses after dilution 1:10 in normal saline by slow intravenous infusion according to the varying infusion rates in Table 1.
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- Monitor vital signs throughout the infusion. If tolerated, the infusion rate can be increased incrementally up to the maximum infusion rate, and continued for the remainder of the administration. Decrease infusion rate if the patient develops discomfort or infusion-related adverse reactions.
