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Bazedoxifene and conjugated estrogens
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Bazedoxifene and conjugated estrogens

Generic name: bazedoxifene and conjugated estrogens [ BA-ze-DOX-i-feen-and-KON-joo-GAY-ted-ES-troe-jens ]
Brand name: Duavee
Dosage form: oral tablet (20 mg-0.45 mg)
Drug class:Sex hormone combinations

Medically reviewed by Drugs.com on Feb 7, 2022. Written by Cerner Multum.

What is bazedoxifene and conjugated estrogens?

Bazedoxifene blocks estrogen from reaching certain cells in the uterine lining, to protect against overgrowth of uterine tissue.

Estrogen is a female sex hormone produced by the ovaries. Conjugated estrogens are a mixture of estrogen hormones.

Bazedoxifene and conjugated estrogens is a combination medicine used short-term in women after menopause to treat moderate to severe hot flashes, and to prevent osteoporosis. bazedoxifene and conjugated estrogens is used in women who have NOT had a hysterectomy (uterus removed).

Bazedoxifene and conjugated estrogens may also be used for purposes not listed in this medication guide.

Warnings

You should not use this medicine if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will have major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.

Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries.Estrogens should not be used to prevent heart disease, stroke, or dementia.

Estrogens may increase your risk of developing a condition that may lead to uterine cancer. Report any unusual vaginal bleeding right away.

Bazedoxifene and conjugated estrogens is for short-term use at the lowest dose needed to treat your condition.

Do not take any other estrogens while you are taking this medicine.

Before taking this medicine

You should not use bazedoxifene and conjugated estrogens if you are allergic to bazedoxifene or conjugated estrogens, or if you have:

  • unusual vaginal bleeding that has not been checked by a doctor;

  • liver disease;

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