Bedaquiline
Generic name: bedaquiline [ bed-AK-wi-leen ]
Brand name: Sirturo
Dosage form: oral tablet (100 mg; 20 mg)
Drug class:Diarylquinolines
What is bedaquiline?
Bedaquiline is an antibiotic that is used together with other medications to treat tuberculosis of the lungs that has been resistant to other antibacterial medications.
Bedaquiline is for use in adults and children at least 5 years old and weighing at least 33 pounds (15 kilograms).
Bedaquiline can cause serious and sometimes fatal side effects. bedaquiline should be used only if you have no other treatment options.
Bedaquiline may also be used for purposes not listed in this medication guide.
Warnings
Bedaquiline can cause serious and sometimes fatal side effects. This medicine should be used only if you have no other treatment options. Use only the prescribed dose of this medication, and follow all patient instructions for safe use.
Bedaquiline can cause a serious side effect on your heart. Tell your doctor if you have fast or irregular heartbeats and sudden dizziness, like you might pass out.
Before taking this medicine
Tell your doctor if you have ever had:
heart problems or a heart rhythm disorder;
long QT syndrome (in you or a family member);
human immunodeficiency virus (HIV);
liver or kidney disease; or
an electrolyte imbalance (such as low blood levels of calcium, potassium, or magnesium in your blood).
Follow your doctor's instructions about using bedaquiline if you are pregnant. Having tuberculosis during pregnancy could harm both mother and baby.
If you are breastfeeding, tell your doctor if you notice decreased appetite, sleepiness, nausea, stomach pain or swelling, dark urine, clay-colored-stools, or yellowing of the skin or eyes in the nursing baby.
How should I take bedaquiline?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
You may receive this medicine in a doctor's office or other clinic setting.
Bedaquiline is usually taken every day for 2 weeks, and then only 3 times per week (at least 48 hours between doses) for the next 22 weeks. Follow your doctor's dosing instructions very carefully. You may need to take fewer tablets for each dose af...
