Brentuximab vedotin
Generic name: brentuximab vedotin [ bren-TUX-i-mab-ve-DOE-tin ]
Brand name: Adcetris
Dosage form: intravenous powder for injection (50 mg)
Drug class:CD30 monoclonal antibodies
What is brentuximab vedotin?
Brentuximab vedotin is used to treat classical Hodgkin lymphoma.
Brentuximab vedotin is also used to treat anaplastic large cell lymphoma that affects organs throughout the body (systemic) or that is confined only to the skin (primary cutaneous).
Brentuximab vedotin is sometimes given after other treatments have failed.
Brentuximab vedotin may also be used for purposes not listed in this medication guide.
Warnings
You should not receive brentuximab vedotin if you are also receiving another cancer medicine called bleomycin.
Brentuximab vedotin may cause a serious brain infection that can lead to disability or death. Call your doctor right away if you have problems with speech, thought, vision, or muscle movement.
Before taking this medicine
You should not be treated with brentuximab vedotin if you are allergic to it, or:
if you are also receiving another cancer medicine called bleomycin.
Tell your doctor if you have ever had:
diabetes;
kidney disease; or
peripheral vascular disease such as Raynaud's syndrome.
Both men and women using this medicine should use effective birth control to prevent pregnancy. Brentuximab vedotin can harm an unborn baby or cause birth defects if the mother or father is using this medicine.
Keep using birth control for at least 6 months after your last dose of brentuximab vedotin. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using brentuximab vedotin.
You should not breast-feed while you are using brentuximab vedotin.
How is brentuximab vedotin given?
Brentuximab vedotin is given as an infusion into a vein. A healthcare provider will give you this injection.
Brentuximab vedotin is usually given once every 2 to 3 weeks. Follow your doctor's dosing instructions very carefully.
You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.
Brentuximab vedotin can lower your blood cell counts. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results.
Brentuximab vedotin doses are based on weight. Y...
