Brevoxyl Gel

Generic name:benzoyl peroxide
Dosage form: gel
Drug class:Topical acne agents

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

AQUEOUS BASE ACNE GEL

FOR TOPICAL USE

Rx only

Brevoxyl Gel Description

Brevoxyl® -4 Gel and Brevoxyl® -8 Gel are topical preparations containing benzoyl peroxide 4% and 8%, respectively, as the active ingredient in a gel vehicle containing ceteareth-20, cetyl alcohol, dimethyl isosorbide, fragrance, purified water, simethicone, stearyl alcohol.

The structural formula of benzoyl peroxide is:

Brevoxyl Gel - Clinical Pharmacology

The exact method of action of benzoyl peroxide in acne vulgaris is not known. Benzoyl peroxide is an antibacterial agent with demonstrated activity against Propionibacterium acnes. This action, combined with the mild keratolytic effect of benzoyl peroxide is believed to be responsible for its usefulness in acne.

Benzoyl peroxide is absorbed by the skin where it is metabolized to benzoic acid and excreted as benzoate in the urine.

Indications and Usage for Brevoxyl Gel

Brevoxyl® -4 Gel and Brevoxyl® -8 Gel are indicated for use in the topical treatment of mild to moderate acne vulgaris. Brevoxyl® -4 Gel or Brevoxyl® -8 Gel may be used as an adjunct in acne treatment regimens including antibiotics, retinoic acid products, and sulfur/salicylic acid containing preparations.

Contraindications

Brevoxyl® -4 Gel and Brevoxyl®