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Breyanzi
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Breyanzi

Generic name:lisocabtagene maraleucel
Dosage form: suspension for intravenous infusion
Drug class:Miscellaneous antineoplastics

Medically reviewed by Judith Stewart, BPharm. Last updated on Sep 1, 2021.

What is Breyanzi?

Breyanzi is for the treatment of large B-cell lymphoma in patients when at least 2 previous treatments have not worked or have stopped working. Breyanzi is a medicine made from your own white blood cells; the cells are genetically modified to recognize and attack your lymphoma cells.

Warnings

Breyanzi may cause side effects that are life-threatening and can lead to death.
Call your healthcare provider or get emergency help right away if you get any of the following:

  • difficulty breathing
  • fever (100.4°F/38°C or higher)
  • chills/shaking chills
  • confusion
  • severe nausea, vomiting, diarrhea
  • fast or irregular heartbeat
  • dizziness/lightheadedness
  • severe fatigue or weakness

It is important that you tell your healthcare providers that you have received Breyanzi and to show them your Patient Wallet Card. Your healthcare provider may give you other medicines to treat your side effects.

How should I use Breyanzi?

  • Breyanzi is made from your own white blood cells, so your blood will be collected by a process called "leukapheresis".
  • It takes about 3-4 weeks from the time your cells are received at the manufacturing site and are available to be shipped back to your healthcare provider, but the time may vary.
  • Before you get Breyanzi, you will get 3 days of chemotherapy to prepare your body.
  • When your Breyanzi is ready, your healthcare provider will give it to you through a catheter (tube) placed into your vein (intravenous infusion). Breyanzi is given as infusions of 2 different cell types.
    • You will receive infusions of one cell type, immediately followed by the other cell type.
    • The time for infusion will va.