Brigatinib
Generic name: brigatinib [ bri-GAT-i-nib ]
Brand name: Alunbrig
Dosage form: oral tablet (180 mg; 30 mg; 90 mg; 90 mg-180 mg)
Drug class:Multikinase inhibitors
What is brigatinib?
Brigatinib is used to treat non-small cell lung cancer that has spread to other parts of the body (metastatic) after other treatments have failed.
Brigatinib is used only if your cancer has a specific genetic marker (an abnormal "ALK" gene). Your doctor will test you for this gene.
Brigatinib may also be used for purposes not listed in this medication guide.
Warnings
Brigatinib can cause serious side effects such as lung problems, vision problems, high blood pressure, high blood sugar, very slow heartbeats, muscle damage, or pancreatitis.
Call your doctor at once if you have side effects, such as: severe headache, confusion, feeling light-headed, blurred vision, seeing flashes of light or "floaters" in your vision, increased thirst or urination, hunger, nausea, upper stomach pain spreading to your back, unexplained muscle pain or weakness, fever, cough, chest pain, trouble breathing, very slow heartbeats, or feeling like you might pass out.
Before taking this medicine
You should not use brigatinib if you are allergic to it.
Tell your doctor if you have ever had:
lung disease or breathing problems;
slow heartbeats;
high blood pressure;
vision problems;
diabetes or glucose intolerance;
pancreas problems;
liver disease; or
kidney disease (or if you are on dialysis).
You may need to have a negative pregnancy test before starting this treatment.
Brigatinib can harm an unborn baby if the mother or the father is using brigatinib.
If you are a woman, do not use this medicine if you are pregnant. Brigatinib can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use an effective non-hormonal form of birth control such as an intrauterine device (IUD). Avoid getting pregnant for at least 4 months after your last dose.
If you are a man, use condoms or other barrier birth control if your sex partner is able to get pregnant. Keep using condoms for at least 3 months after your last dose.
Tell your d...
