Brimonidine, Timolol Eye Drops

Generic name: brimonidine tartrate, timolol maleate
Dosage form: ophthalmic solution
Drug class:Ophthalmic glaucoma agents

Medically reviewed by Drugs.com. Last updated on Aug 1, 2021.

Indications and Usage for Brimonidine, Timolol Eye Drops

Brimonidine tartrate and timolol maleate ophthalmic solution, 0.2%/0.5% is an alpha-adrenergic receptor agonist with a beta-adrenergic receptor inhibitor indicated for the reduction of elevated intraocular pressure (IOP) in patients with ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP; the IOP-lowering of brimonidine tartrate and timolol maleate ophthalmic solution, 0.2%/0.5% dosed twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol maleate ophthalmic solution dosed twice a day and 0.2% brimonidine tartrate ophthalmic solution dosed three times per day.

Brimonidine, Timolol Eye Drops Dosage and Administration

The recommended dose is one drop of brimonidine tartrate and timolol maleate ophthalmic solution, 0.2%/0.5% in the affected eye(s) twice daily approximately 12 hours apart. If more than one topical ophthalmic product is to be used, the different products should be instilled at least 5 minutes apart.

Dosage Forms and Strengths

Solution containing 2 mg/mL brimonidine tartrate and 5 mg/mL timolol (6.8 mg/mL timolol maleate).

Contraindications

Reactive Airway Disease Including Asthma, COPD

Brimonidine tartrate and timolol maleate ophthalmic solution, 0.2%/0.5% is contraindicated in patients with reactive airway disease including bronchial asthma; a history of bronchial asthma; severe chronic obstructive pulmonary disease [see Warnings and Pre...