Brincidofovir (Oral)
Medically reviewed by Drugs.com. Last updated on Mar 18, 2022.
Warning: Increased Risk for Mortality When Used for Longer DurationAn increased incidence of mortality was seen in brincidofovir-treated subjects compared to placebo-treated subjects in a 24-week clinical trail when brincidofovir was evaluated in another disease .
Commonly used brand name(s)
In the U.S.
- Tembexa
Uses for brincidofovir
Brincidofovir is used to treat human smallpox disease caused by the variola virus.
Brincidofovir is available only with your doctor's prescription.
Before using brincidofovir
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For brincidofovir, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to brincidofovir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of brincidofovir in the pediatric population.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of brincidofovir in the elderly.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of brincidofovir. Make sure you tell your doctor if you have any other medical problems, especially:
- Liver disease—Use with caution. May make this condition worse.
- Weak immune system—Use with caution. May increase risk for serious side effects.
Proper use of brincidofovir
Take brincidofovir only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.
Brincidofovir comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.
To use ..
